A REVIEW OF TWO AMBIGUITIES IN THE NOVEL "THE ADVENTURES OF HAJJI BABA ISFAHANI"


Silencing of PARP2 Blocks Autophagic Degradation

Poly(ADP-Ribose) polymerases (PARPs) are enzymes that metabolize NAD+.PARP1 and PARP10 were previously implicated in the regulation of autophagy.Here we showed that cytosolic electron-dense particles appear in the cytoplasm of C2C12 myoblasts in which PARP2 is silenced by shRNA.The cytosolic electron-dense bodies resemble autophagic vesicles and, i

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Brief Myocardial Ischemia Produces Cardiac Troponin I Release and Focal Myocyte Apoptosis in the Absence of Pathological Infarction in Swine

Summary: In a porcine model of brief ischemia leading to reversible stunning in the absence of tissue necrosis, we demonstrated delayed release of cardiac troponin I (cTnI) that exceeded the 99th percentile for normal animals 60 min after Tie Clip reperfusion and rose to readily detectable levels 24 h later.Although tissue analysis at 60 min showed

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Are dogs with congenital hearing and/or vision impairments so different from sensory normal dogs? A survey of demographics, morphology, health, behaviour, communication, and activities.

The births of domestic dogs with pigment deletion and associated congenital hearing and/or vision impairments are increasing, as a result of mutations of certain genes expressing popular coat colour patterns (Merle, piebald, Irish spotting).The future of these dogs is often pessimistic (early euthanasia or placement in rescues/fosters, lack of inte

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